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Title: Bio Iinformatics The Emerging Discipline
Description: Bio Iinformatics The Emerging Discipline

Bioinformatics is a new engineering field served by traditional engineering curricula. Bioinformatics can be defined in several ways, but the emphasis is always on the use of computer and statistical methods to understand biological data, such as the voluminous data produced by high-throughput biological experimentation including gene sequencing and gene chips. Bioinformatics, the application of computational techniques to analyze the information associated with bimolecular on a large-scale, has now firmly established itself as a discipline in molecular biology, and encompasses a wide range of subject areas from structural biology, genomics to gene expression studies.

Bioinformatics is an integration of mathematical,statistical and computer metods to analyze biological,biochemical and biophysical data.

In this review we provide an introduction and overview of the current state of the field.... Bioinformatics, its applications and advantages and finally we conclude that Science is a never-ending story. The solution of one mystery is the seed of many others. Bioinformatics should be an important component of biotechnology education and it should be taught from a broad-based platform. Bioinformatics is an essential component of modern biology and not independent of it. The whole area of biology can immensely benefit from the bioinformatics approach.

KEYWORDS:

Gene sequencing, Genomics, Databases, Data Management, Proteomics, Geom., Proteome, Transcriptomics, Metabalomics, Glycomics, Nucleotide, Data gatherers, Dataprocessers, Molecular Phylogenies.

1. INTRODUCTION

1. a) DEFINITION

Bioinformatics is the application of quantitative and analytical computational techniques to model biological systems. It is the buzzword of the current times. If biotechnology is hot, bioinformatics is its hottest arm, shrouded in a lot of hype, with conveniently concealed ground realities. It is necessary that bioinformatics is viewed in the proper perspective in order to reap the rich benefits that accrue out of it.

The term bioinformatics is the short form of biological informatics, just as biotechnology is the short form of biological technology.

Bioinformatics can be defined as any application of computation to the field of biology, including data management, algorithm development, and data mining.

A database is meant to store voluminous information in an orderly fashion, to facilitate addition and/or deletion of information and to provide for its retrieval in any one or more of several different permutations and combinations as desired by the user used it in different contexts.

1.b)A BRIEF HISTORY OF BIOINFORMATICS:

Bioinformatics has emerged out of the inputs of specialists from several different areas such as biology, biochemistry, biophysics, molecular biology, and biostatistics and computer science. Specially designed algorithms and organized computer databases are at the core of all bioinformatics operations. Algorithms, that are necessarily complex, make voluminous data easy to handle for defined purposes, in an amazingly short time, a process that is humanly impossible. The requirements of such an activity make heavy and high level demands on both the hardware and the software capabilities of computers.

1.c)BIOINFORMATICS COMPRISES OF:

Bioinformatics encompasses the use of tools and techniques from three separate disciplines; molecular biology (the source of the data to be analyzed), computer science (supplies the hardware for running analysis and the networks to communicate the results), and the data analysis algorithms which strictly define Bioinformatics.

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